本帖最后由 猫狼血泪 于 2014-6-5 03:31 编辑
嘛，好久没回来了，一回来就看见各种...........危险的东西...........
什么时候我的地位被动摇了！没人告诉我啊！
切
只有自己找回场子了
嘛
上次
好吧
很久很久之前
好吧
其实是去年
说好的固体酒精呢，我坑了
恩
嘛，我是编故事的弃坑什么的最习惯了对吧~对吧~对吧~
$54$
好啦好啦，不要闹了，我来了，肯定有好东西了对吧
不过还是不放图不放比例
这次我还要缩减到不放详细做法
$75$
屠龙你会原谅我对吧
于是乎
猫狼先生
向你
郑重介绍
闪光弹君~~~~~~~~
（撒花）
（鼓掌）
（尖叫）
咳咳
材料为：铝条，火药（做不来的，或者不想做的，买鞭炮吧，别摔炮，不然真的挺好玩的= =），方便面，开水（我想大约在九十度以上，也就是最少要饮水机里面的开水），想玩大点的，自己加镁条........
工具为：锉子，筷子。
容器为：纸盒子，碗
制作工序大概为：1、用锉子把铝条弄成粉末，越细越好= =
2、把粉末装进小纸盒里面
3、把火药装进小纸盒里面
4、混合.......（用锉子就好了不要用筷子，千万不要用筷子！不然你会后悔的！）
千万要记住，不要用筷子混合两种粉末，不管什么材质的筷子！确定没有用了后，继续看下面的吧= =
5、打开方便面包装
6、用碗装好方便面的面饼，调料，和热水
7、找个东西盖好碗（不要用装有粉末的小纸盒，千万不要用）
8、在小纸盒里面放个可以燃烧的东西，比如说纸啊什么的，当引线，然后盖上，用胶带什么的封好
9、空旷的，室外，点燃
10、边看强烈的闪光边吃着你泡好的方便面吧= =
没有比例，没有图
因为我懒啊~
话说忘了字体怎么改大小了好桑心
这里是依旧无厘头无笑点不正常的猫狼三三
你们好吗~
$45$
我一点也不好
因为
好累啊
$56$
不叫人了，自己能看见就来打声招呼吧= =

LSD-25 Synthesisfrom "Psychedelic Guide to the Preparation of the Eucharist"
Preparatory arrangements
Starting material may be any lysergic acidderivative, from ergot on rye grain or from culture, or morning glory seeds orfrom synthetic sources. Preparation #1 uses any amide, or lysergic acid asstarting material. Preparations #2 and #3 must start with lysergic acid only,prepared from the amides as follows:
10 g of any lysergic acid amide from variousnatural sources dissolved in 200 ml of methanolic KOH solution and the methanolremoved immediately in vacuo. The residue is treated with 200 ml of an 8%aqueous solution of KOH and the mixture heated on a steam bath for one hour. Astream of nitrogen gas is passed through the flask during heating and theevolved NH3 gas may be titrated is HCl to follow the reaction. The alkalinesolution is made neutral to congo red with tartaric acid, filtered, cleaned byextraction with ether, the aqueous solution filtered and evaporated. Digestwith MeOH to remove some of the coloured material from the crystals of lysergicacid.
Arrange the lighting in the lab similarly to thatof a dark room. Use photographic red and yellow safety lights, as lysergic acidderivatives are decomposed when light is present. Rubber gloves must be worndue to the highly poisonous nature of ergot alkaloids. A hair drier, or,better, a flash evaporator, is necessary to speed up steps where evaporation isnecessary.
--------------------------------------------------------------------------------
Preparation #1
Step I. Use Yellow light
Place one volume of powdered ergot alkaloidmaterial in a tiny roundbottom flask and add two volumes of anhydroushydrazine. An alternate procedure uses a sealed tube in which the reagents areheated at 112 C. The mixture is refluxed (or heated) for 30 minutes. Add 1.5volumes of H2O and boil 15 minutes. On cooling in the refrigerator, isolysergicacid hydrazide is crystallised.
Step II. Use Red light
Chill all reagents and have ice handy. Dissolve2.82 g hydrazine rapidly in 100 ml 0.1 N ice-cold HCl using an ice bath to keepthe reaction vessel at 0 C. 100 ml ice-cold 0.1 N NaNO2 is added and after 2 to3 minutes vigorous stirring, 130 ml more HCl is added dropwise with vigorousstirring again in an ice bath. After 5 minutes, neutralise the solution withNaHCO3 saturated sol. and extract with ether. Remove the aqueous solution andtry to dissolve the gummy substance in ether. Adjust the ether solution byadding 3 g diethylamine per 300 ml ether extract. Allow to stand in the dark,gradually warming up to 20 C over a period of 24 hours. Evaporate in vacuum andtreat as indicated in the purification section for conversion of iso-lysergicamides to lysergic acid amides.
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Preparation #2
Step I. Use Yellow light
5.36 g of d-lysergic acid are suspended in 125ml of acetonitrile and the suspension cooled to about -20 C in a bath ofacetone cooled with dry ice. To the suspension is added a cold (-20 C) solutionof 8.82 g of trifluoroacetic anhydride in 75 ml of acetonitrile. The mixture isallowed to stand at -20 C for about 1.5 hours during which the suspendedmaterial dissolves, and the d-lysergic acid is converted to the mixed anhydrideof lysergic and trifluoroacetic acids. The mixed anhydride can be separated inthe form of an oil by evaporating the solvent in vacuo at a temperature below 0C, but this is not necessary. Everything must be kept anhydrous. 
Step II. UseYellow light
The solution of mixed anhydrides in acetonitrilefrom Step I is added to 150 ml of a second solution of acetonitrile containing7.6 g of diethylamine. The mixture is held in the dark at room temperature forabout 2 hours. The acetonitrile is evaporated in vacuo, leaving a residue ofLSD-25 plus other impurities. The residue is dissolved in 150 ml of chloroformand 20 ml of ice water. The chloroform layer is removed and the aqueous layeris extracted with several portions of chloroform. The chloroform portions arecombined and in turn washed with four 50 ml portions of ice-cold water. Thechloroform solution is then dried over anhydrous Na2SO4 and evaporated invacuo.
--------------------------------------------------------------------------------
Preparation #3
This procedure gives good yield and is very fastwith little iso-lysergic acid being formed (its effect are mildly unpleasant).However, the stoichometry must be exact or yields will drop.
Step I. Use White light
Sulfur trioxide is produced in anhydrous stateby carefully decomposing anhydrous ferric sulfate at approximately 480 C. Storeunder anhydrous conditions.
Step II. Use White light
A carefully dried 22 litre RB flask fitted withan ice bath, condenser, dropping funnel and mechanical stirrer is charged with10 to 11 litres of dimethylformamide (freshly distilled under reducedpressure). The condenser and dropping funnel are both protected againstatmospheric moisture. 2 lb of sulfur trioxide (Sulfan B) are introduceddropwise, very cautiously stirring, during 4 to 5 hours. The temperature is keptat 0-5 C throughout the addition. After the addition is complete, the mixtureis stirred for 1-2 hours until some separated, crystalline sulfurtrioxide-dimethylformamide complex has dissolved. The reagent is transferred toan air- tight automatic pipette for convenient dispensing, and kept in thecold. Although the reagent, which is colourless, may change from yellow to red,its efficiency remains unimpaired for three to four months in cold storage. Analiquot is dissolved in water and titrated with standard NaOH to aphenolphthalein end point.
Step III. Use Red light
A solution of 7.15 g of d-lysergic acid monohydrate (25 mmol) and 1.06 g of lithium hydroxide hydrate (25 mmol) in 200 mlof MeOH is prepared. The solvent is distilled on the steam bath under reducedpressure. the residue of glass-like lithium lysergate is dissolved in 400 ml ofanhydrous dimethyl formamide. From this solution about 200 ml of the dimethylformamide is distilled off at 15 ml pressure through a 12 inch helices packedcolumn. the resulting anhydrous solution of lithium lysergate left behind iscooled to 0 C and, with stirring, treated rapidly with 500 ml of SO3-DMFsolution (1.00 molar). The mixture is stirred in the cold for 10 minutes andthen 9.14 g (125.0 mmol) of diethylamine is added. The stirring and cooling arecontinued for 10 minutes longer, when 400 ml of water is added to decompose thereaction complex. After mixing thoroughly, 200 ml of saturated aqueous salinesolution is added. The amide product is isolated by repeated extraction with500 ml portions of ethylene dichloride. the combined extract is dried and thenconcentrated to a syrup under reduced pressure. Do not heat up the syrup duringconcentration. the LSD may crystallise out, but the crystals and the motherliquor may be chromatographed according to the instructions on purification. 
--------------------------------------------------------------------------------
Purification of LSD-25
The material obtained by any of these threepreparations may contain both lysergic acid and iso-lysergic acid amides.Preparation #1 contains mostly iso-lysergic diethylamide and must be convertedprior to separation. For this material, go to Step II first.
Step I
Use darkroom and follow with a long wave UV Thematerial is dissolved in a 3:1 mixture of benzene and chloroform. Pack thechromatography column with a slurry of basic alumina in benzene so that a 1inch column is six inches long. Drain the solvent to the top of the aluminacolumn and carefully add an aliquot of the LSD-solvent solution containing 50ml of solvent and 1 g LSD. Run this through the column, following the fastestmoving fluorescent band. After it has been collected, strip the remainingmaterial from the column by washing with MeOH. Use the UV light sparingly toprevent excessive damage to the compounds. Evaporate the second fraction invacuo and set aside for Step II. The fraction containing the pure LSD isconcentrated in vacuo and the syrup will crystallise slowly. This material maybe converted to the tartrate by tartaric acid and the LSD tartrate convenientlycrystallised. MP 190-196 C.
Step II. Use Red light
Dissolve the residue derived from the methanolstripping of the column in a minimum amount of alcohol. Add twice that volumeof 4 N alcoholic KOH solution and allow the mixture to stand at roomtemperature for several hours. Neutralise with dilute HCl, make slightly basicwith NH4OH and extract with chloroform or ethylene dichloride as inpreparations #1 or #2. Evaporate in vacuo and chromatograph as in the previousstep.
Lysergic acid compounds are unstable to heat,light and oxygen. In any form it helps to add ascorbic acid as an anti-oxidant, keeping the container tightly closed, light-tight with aluminum foil,and in a refrigerator.
--------------------------------------------------------------------------------
Synthesis of d-LSD maleate or tartrate fromlysergic acid with POCl3
Ref:
Johnson, Ary, Teiger, Kassel. "EmeticActivity of Reduced Lysergamides." Journal of Medicinal Chemistry.16(5):532-537. 1973.
Related:
Huang, Marona-Lewicka, Pfaff, Nichols."Drug Discrimination and Receptor Binding Studies of N-IsopropylLysergamide Derivates." Pharmacology, Biochmistry and Behavior.47(3):667-673, 1994.
Oberlender, Pfaff, Johnson, Huang, Nichols."Stereoselective LSD-like Activity in d-Lysergic Acid Amides of (R)- and(S)-2-Aminobutane." Journal of Medicinal Chemistry. 35(2):203-211, 1992.
Hoffman-AJ, Nichols. "Synthesis andLSD-like Descriminative Stimulus Properties in a Series of N(6)-alkylNorlysergic Acid N,N-Diethylamide Derivates." Journal of MedicinalChemistry. 28:1252-1255, 1985.
NOTE: JMC 35(2):203-211 has some amazingstereoviews of LSD which might interest non-chemists who like to cross theireyes. 
Under reducedlight (or red light) a stirred solution of 3.15g (11 mmol) of d-lysergic acidmonohydrate and 4.45g (99 mmol) of diethylamine was brought to reflux byheating. Heat was removed, and reflux was maintained by the addition of 2ml(3.4g, 22mmol) of phosphorous oxychloride (POCl3) over a 2 minute period. Themixture was then refluxed for an additional 4-5 mins until an amber-coloredsolution resulted. The solution was brought to room temperature and was washedwith 200ml of 1M NH4OH. The CHCl3 solution was dried (MgSO4), filtered, andconcentrated under vacuum (not allowing the solution to exceed 40 degrees C).The last traces of the solvent were removed at 2-5 mm. The viscious residue wasdissolved in a minimum amount of MeOH and acidified with a freshly prepared 20%solution of maleic acid in MeOH. Crystallization occured spontaneously. Theneedles were filtered, washed with cold MeOH and air-dried. Yield was 66% afterfurther purification by column chromatography over alumina (Brockman) andelution with 3:1 benzene-chloroform. The chromatography takes appx 8-9 hours.Alternatively, it can be crystallized as the (+)-tartrate from MeOH. Aftercrystallizing from cold MeOH, it is diluted with ethyl acetate, filtered andthe the crystals are washed with ethyl acetate. 
This procedure also works for primary amines andsmall dialkyl amines. LSD, however, probably remains the most worthwhileproduct. Other interesting amines might be the N-ethyl-N-propyl derivative(LEP) and the morpholide (LSM-775). 75ug of the morpholide have been reportedto have been as effective as 50ug of d-LSD but with 45 min onset (vs 1 hour)and a 1 hour peak (vs 4 hours). The procedure would probably work well for LEP,but yields would be reduced for the morpholide. Other N(20)-alkyl-lysergic acidderivatives tend to be more than 10 times less potent than LSD if noteffectively inactive. N(6)-ethyl- (and -allyl- and -propyl-) derivates of LSDmay be more active than LSD itself, but synthetic routes to these chemicalspresently start with LSD and yields would probably inhibit their appearance onthe illicit market. (N(6) is the other nitrogen on the ring structure inaddition to the N(1) pyrrole/indole nitrogen). Derivatives of LSD (besidesLSA/LA-111 and lysergic acid) are not scheduled, but would be prosecutableunder the designer drugs act after testimony from a DEA agent that _in theiropinion_ the defendant was planning to distribute them.  

我没学过化学  求资料    最好是入门的资料   还有 化学需要用到的东西在哪里能买到

最近在做课程设计，在硒的检测中需要3，3 一二氨基联苯胺溶液，可是我在实验室试了一下发现这种物质是很难于水（有文献说要超声波溶解，待会我试试怕是不太可能），有文献说要溶解在四氯化碳中，可是发现也是无法溶解的。实验赶得有些着急所以也就请大家帮忙咯

2012年 Fukuyama Group的合成题。新人刷下存在感吧。答案和其他年的，私聊啊什么的。
新人求脸熟⊙０⊙

授权
开始帖子
洗瓶，烧杯，试管刷，试管，胶头滴管，集气瓶，玻璃片，电子称，药勺是我们要用到的仪器
硝酸银，氢氧化钠，葡萄糖，浓氨水
这些是我们需要的药品（这里楼主我用的是小瓶的硝酸银，大瓶的就不拿出来了）
首先，量取１ｇ硝酸银（ＡｇＮＯ３），虽然标准的是配置２％的硝酸银溶液，但是为了提高成功率，所以稍微提升浓度配置２．５～３％左右的硝酸银溶液（加４０ｍｌ水即可），因为硝酸银含量过低会导致镀银过薄
如图，配置好的硝酸银溶液，但是楼主这个怎么莫名其妙的白了．．．难不成分解了？？？好奇怪
下一步就反反复复的清洗试管，先用自来水冲洗，并用试管刷配合清洗试管内壁，最后并用蒸馏水冲洗试管，直到试管内壁是均匀的水膜，而不是水滴成股流下就可以了，这是标准规范的清洗办法，然后进行甩干
向洗净的试管中倒入硝酸银溶液
向集气瓶内倒入浓氨水（我的是２６％左右的），并盖上玻璃片，氨水的味道十分刺激，对眼睛和鼻子都有清冽刺激，所以请做好通风和防护工作
这，是配置好的氢氧化钠溶液，这个唯一的浓度要求就是不要太稀，所以配置个大概就好了。我配置的是２５％的氢氧化钠溶液
这是楼主配置的葡萄糖溶液，也是没有浓度要求，但是不可以过于稀，这个用饱和溶液都可以
向硝酸银溶液中滴加氢氧化钠溶液产生棕色沉淀（如图）
再向试管中缓慢滴加浓氨水并震荡，直至沉淀恰好消失
然后准备一杯开水，后面做水浴用
然后加入适量的葡萄糖溶液，并将试管迅速插入准备好的开水中，你就会发现试管内溶液开始渐渐变黄，然后颜色越来越深
越来越深
如图，当试管中的液体颜色变黑后，下一步试管上就会开始微微泛出银白色，随着时间越来越长，就会看到一层非常光亮的银了，注意千万不要震动
过５ｍｉｎ左右，就可以将试管取出，并用温水冲洗试管里面，将黑色沉淀洗净，并拿去晾干了
这根大的是我用剩下的药品做的，后面的小西林瓶的那个也是
这几个是最近做的
搬运有话说：原PO简直壕无人性...我这种穷人就看看吧...

上次的帖子图太少，字太多，注定沉，这次发个图鉴贴弥补一下上次的。
上授权
开始！
搬运完毕，希望对大家有帮助

本帖最后由 吾有屠龙之术 于 2014-2-17 20:12 编辑
寒假终于结束了，不知小伙伴们过得咋样？一定又虚度了吧2333333@29#
春节过得肿么样，一定又胖了吧2333333@29#
作业做得肿么样？一定又是最后两天熬夜做的吧23333@29#
话说初中党高中党还有摸底考试吧2333333@29#
你们感受一下和寒假生死相离了的小生的恶意……
随着寒假的结束，化学实验室的寒假活动也结束了，就让小生来公布答案吧！
第一题：
答案：Ca(ClO)2+CO2+H2O====CaCO3↓+2HClO
可乐是碳酸饮料，那必然是CO2，白色的粉末状，小生在提示里说过是“漂白粉”，其主要成分就是次氯酸钙。
第二题：
答案：2Cs+2H2O====2CsOH+H2↑
Cs是金属元素铯的化学符号。铯的化学性质与同为第一主族的钾、铷相似，与水反应最剧烈。
氢氧化铯溶液是无色的，所以图中应该滴了酚酞吧？（小生只能想到酚酞……）
第三题：
答案：Fe+CuSO4====FeSO4+Cu
小生明明已经提示了：图是错的……可还是有好多同学中招……
置换反应一定是活泼金属置换不活泼的啦！
第四题：
答案：2Hg(SCN)2＝=△=＝2HgS＋CS2＋C3N4
或者4Hg(SCN)₂ =4HgS + 2CS₂ + 3(CN)₂↑ + N₂↑
这就是著名的“法老飞蛇”试验啦，以上两个答案都算正确！
第五题：
答案：4Li+O2==点燃==2Li2O
锂也是碱金属，所以即使没学习过它的性质也可以按照钠来写
第六题：
答案：章鱼
章鱼和乌贼的差别就在于有几条触手
这个小生数来数去都觉得只有八条触手，所以只算章鱼的答案，没算乌贼的！
八爪鱼这么萌的答案当然不能算啦！